孤独症谱系障碍的病因研究进展

Recent Advances of Etiology of Autism Spectrum Disorders

孤独症谱系障碍(autism spectrum disorders,ASD)是一组以社交沟通障碍、兴趣或活动范围狭窄以及重复刻板行为为主要特征的神经发育性障碍。于1943年由美国儿童精神病学家Kanner首先报道。近年来,随着对ASD病因研究的深入,以及相关循证报道的增多,现趋向认为ASD多个因素共同作用结果。从环境和遗传两个方面对ASD病因学进行综述。

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by social communication disorder, narrow range of interest or activity and repeated stereotyped behavior. It was first reported by Kanner, an American child psychiatrist, in 1943. There are more and more studies on the etiologies of ASD. The etiology of ASD is multi-factorial background, which becomes research hot spots recently. In the present paper, we provide a review of the current research about environmental factors and genetic factors in ASD.