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低分子肝素治疗小儿重症肺炎对潮气呼吸肺功能的影响观察 被引量:3

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摘要 目的观察低分子肝素辅助治疗对重症肺炎患儿潮气呼吸肺功能的影响。方法选择重症肺炎患儿90例,采用随机数字表法分为对照组、观察组,各45例;选取同期于我院进行健康体检婴幼儿45例为空白对照组。对照组以布地奈德及对症支持治疗,观察组在此基础上应用低分子肝素。测定三组治疗前后潮气呼吸肺功能指标;对比两组患儿临床症状、体征消失时间及治疗期间出血情况。结果治疗前,对照组与观察组RR高于空白对照组,TV、T_I/T_E、T_I、T_E、V_(PEF)/V_E均低于空白对照组(P均<0. 05);治疗后,对照组与观察组RR低于本组疗前,TV、T_I/T_E、T_I、T_E、V_(PEF)/V_E均高于本组治疗前(P均<0. 05);观察组V_(PEF)/V_E高于对照组(P <0. 05);对照组与观察组RR高于空白对照组(P <0. 05)。观察组咳嗽、肺部湿啰音等临床症状及体征消失时间均短于对照组(P均<0. 05)。治疗过程中两组出血发生率对比,差异无统计学意义(P> 0. 05)。结论低分子肝素联合布地奈德治疗小儿重症肺炎,有助于改善患儿潮气呼吸肺功,利于加快症状及体征消失,应用价值显著,值得临床推广应用。
出处 《湖北科技学院学报(医学版)》 2019年第1期39-41,共3页 Journal of Hubei University of Science and Technology(Medical Sciences)
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