降钙素原及C反应蛋白在儿童肺炎支原体肺炎中的变化及临床意义

Changes and Clinical Significance of Procalcitonin and C-Reactive Protein in Children with Mycoplasma Pneumoniae Pneumonia

目的:探讨肺炎支原体肺炎(MPP)患儿降钙素原(PCT)及C反应蛋白(CRP)的变化对其早期诊断的临床指导意义。方法:选取肺炎支原体肺炎患儿35例,细菌性肺炎患儿40例,另外选择30例健康儿童作为正常对照组。检测并分析比较各组的PCT及CRP水平。结果:与健康对照组比较,支原体肺炎组PCT及CRP水平明显升高,但增高程度不如细菌肺炎组,差异均有统计学意义(P <0. 05)。结论:联合检测血清PCT、CRP有助于MPP早期诊断、感染程度以及疗效的监测。

Objective:To explore the clinical significance in early diagnosis for the changes of procalcitonin(PCT)and C-reactive protein(CRP)in children with mycoplasma pneumoniae(MPP).Methods:Thirty-five children with mycoplasma pneumoniae and 40 children with bacterial pneumonia were selected.Another 30 healthy children were selected as the normal control group.The levels of PCT and CRP in each group were compared and analyzed.Results:compared with the healthy control group.The levels of PCT and CRP in the mycoplasma pneumonia group were significantly higher,but not higher than those in the bacterial pneumonia group.The differences has statistical significance(P<0.05).Conclusions:Combined detection of serum PCT and CRP is helpful for the early diagnosis of MPP and the monitoring in the degree of infection and efficacy.