子宫内膜增生管理策略变迁

The change of management strategy in endometrial hyperplasia

子宫内膜增生是指子宫内膜腺体的不规则增殖,同时伴有腺体、间质比例增加的器质性疾病。这种疾病通常是由于生殖内分泌紊乱所导致,与长期雌激素刺激而无孕激素对抗密切相关。近年来,随着研究的不断深入,有关子宫内膜增生的处理与管理的观点有所更新和改变。文章结合相关文献,主要围绕子宫内膜增生的分类变化、诊断性刮宫术指征的变化、子宫内膜增生管理观点的改变等几个方面进行论述。

Endometrial hyperplasia is an organic disorder characterized by irregular proliferation of endometrial glands with an increased proportion of glands and stroma. The disease is usually caused by reproductive endocrine disturbances and is closely related to long-term estrogen stimulation without progestin antagonism. In recent years, with the deepening of study, the treatment and management viewpoints of endometrial hyperplasia have been updated and changed. A literature review will be made in this paper with the focus on the issues as follow: classification change of endometrial hyperplasia, the curettage indication changes of endometrial hyperplasia, and the management viewpoint change of endometrial hyperplasia.