超声检查评估帕金森病患者的吞咽功能障碍

Assessment of Dysphagia in Patients with Parkinson Disease:Use of Ultrasonography

目的:超声评价帕金森病(PD)患者的吞咽运动。方法:选取有吞咽障碍的PD患者38例为PD组,另选取40例无任何吞咽障碍的后循环缺血病人为对照组,超声检测各组受试者空咽及吞咽5 m L水时口腔期及咽期的运动时间,并进行组间比较,Logistic回归分析PD患者吞咽功能的影响因素。结果:PD组受试者空咽及吞咽5 m L水时口腔期及咽期的运动时间均明显长于对照组受试者,差异有统计学意义(P <0. 05); Logistic回归分析显示病程和Hoehn-Yahr分级是影响PD病人吞咽功能的危险因素。结论:B/M型超声能够用于评估吞咽功能,安全无创,有吞咽障碍的PD患者的吞咽时间在口腔期、咽期较无吞咽障碍者延长。

Objective:To evaluate the swallowing movement in patients with Parkinson disease(PD)by ultrasonography.Methods:38 patients with PD were selected.The patients all had dysphagia.40 patients with posterior circulation ischemia without dysphagia were selected as the control group.Ultrasonography was used to detect the movement time of the oral and pharyngeal phase when just swallowing and swallowing 5 mL of water in each group of subjects.Comparisons were conducted between groups and Logistic regression was used to analyze the influencing factors of swallowing function in Patients with PD.Results:The duration of oral and pharyngeal movements in the PD group was significantly longer than that in the control group(P<0.05).The results of Logistic regression analysis showed that disease duration and Hoehn and Yahr scale is a risk factor affecting swallowing function in patients with PD.Conclusion:B/M mode ultrasonography which is safe and non-invasive can be used to evaluate the swallowing function.The swallowing time of patients with PD was prolonged during oral and pharyngeal phase.