雾化吸入布地奈德和地塞米松治疗小儿急性喉炎并呼吸困难临床疗效分析

Clinical Efficacy of Nebulized Inhaled Budesonide and Dexamethasone in Children with Acute Laryngitis and Dyspnea

目的:研究分析雾化吸入布地奈德和地塞米松在临床中治疗小儿急性喉炎并呼吸困难的效果。方法:选择于2016年7月～2017年6月期间到某院接受治疗的94例小儿急性喉炎并呼吸困难患儿,遵守随机分配法则,平均分为对照组(n=47)与观察组(n=47)。对照组行滴注地塞米松治疗,观察组行雾化吸入布地奈德治疗,比较两组患儿治疗后的临床疗效、多项症状消失时间、住院时间以及不良反应情况。结果:两组患儿治疗后的临床疗效比较,差异存在统计学意义(P<0.05);除呼吸困难以外,观察组咳嗽、声音嘶哑、吸气性喉鸣以及住院时间均显著优于对照组,差异存在统计学意义(P<0.05);两组患儿不良反应发生率比较,差异不存在统计学意义(P>0.05)。结论:在临床中治疗小儿急性喉炎并呼吸困难患儿的时候,选择雾化吸入布地奈德的效果比静脉滴注地塞米松效果显著,而且症状消失时间短,不良反应发生率无差异,对其生命健康而言具有保障性,应当推广。

Objective:To study the effect of nebulized inhaled budesonide and dexamethasone in the treatment of children with acute laryngitis and dyspnea.Methods:A total of 94 children with acute laryngitis and dyspnea treated in a hospital from July 2016 to June 2017 were selected and randomized according to the method of random distribution to control group(n=47)and observation group(n=47).The control group was treated with dexamethasone.The observation group was treated with aerosolized inhaled budesonide.The clinical efficacy,time of symptoms disappeared,hospitalization time,and adverse reactions of the two groups after treatment were compared.Results:There was a statistically significant difference in clinical efficacy between the two groups of patients after treatment(P<0.05).Except for breathing difficulties,the observation group had significantly better cough,hoarseness,inspiratory laryngeal and hospital stay than the control group.The difference was statistically significant(P<0.05).The difference in the incidence of adverse reactions between the two groups did not exist,with no statistical significance(P>0.05).Conclusion:In the clinical treatment of children with acute laryngitis and dyspnea,the choice of inhaled budesonide is significantly more effective than intravenous infusion of dexamethasone,and the symptoms disappear shortly and the incidence of adverse reactions is low.It is guaranteed for its life and health and should be promoted.