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WAVE2在消化道喉鳞状细胞癌组织中的表达及临床意义

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摘要 目的:探讨WAVE2在消化道喉鳞状细胞癌组织中的表达及临床意义。方法:选取55例喉鳞状细胞癌患者作为研究对象,采用免疫组织化学方法检测55例患者消化道中喉癌组织中WAVE2蛋白的表达;采用Westernblot检测WAVE2蛋白在喉癌组和癌旁黏膜组织中的表达情况。结果:55例喉癌组织中有32例发现有WAVE2蛋白阳性表达,阳性表达率为58.2%;有23例喉癌组织中未见WAVE2蛋白表达,阴性表达率为41.8%。且喉癌组织中WAVE2蛋白表达显著高于癌旁黏膜组织(P<0.05)。WAVE2蛋白表达与临床分期、肿瘤大小和淋巴结转移等临床病理特征有显著相关性。结论:WAVE2在消化道喉鳞状细胞癌组织中高表达且与多种临床病理特征相关。
作者 要兆旭
出处 《现代消化及介入诊疗》 2018年第A02期109-109,共1页 Modern Interventional Diagnosis and Treatment in Gastroenterology
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