阿卡如化学成分研究

Study on Chemical Ingredients of Akaru

目的:研究阿卡如的化学成分。方法:采用现代分离方法和色谱技术,对阿卡如乙酸乙酯部位进行分离纯化,采用波谱技术和理化常数对照等方法进行结构鉴定。结果:从阿卡如乙酸乙酯部分分离并鉴定了6个含量相对较高的化合物,分别为3,4-Di-(3-methoxy-4-hydroxyphenyl)tetrahydrofuran(1),开环异落叶松树脂酚(2),3,3'-dimethoxy-8,9-epoxylign-4,4',9'-triol(3),2S,3S,4S-2-羟基-3,4-二-(3,甲氧基-4-羟基苄基)四氢呋喃(4),2-(3,4-次甲二氧基苄基)-3-(3-甲氧基-4-羟基苄基)-1,4-丁二醇(5),2R,3S,4S-2-羟基-3,4-二-(3,4-次甲二氧基苄基)四氢呋喃(6)。结论:首次从该种植物中分离得到化合物1、2、3、5,首次从该植物主干和根中分离得到化合物4和6。

Objective:To study chemical ingredients of akaru.Methods:By adopting modern separation method and chromatographic technique,the part of acetic ether was separated and purified from akaru,and the structure was identified by spectrum technique and physicochemical constant control method.Results:The part of acetic ether was isolated from akaru,and six compounds in higher contents relatively were identified,they were 3,4-Di-(3-methoxy-4-hydroxyphenyl)tetrahydrofuran(1),Secoisolariciresinol(2),3,3'-dimethoxy-8,9-epoxylign-4,4',9'-triol(3),2S,3S,4S-2-Hydroxy-3,4-di-(3-methoxy-4-hydroxyphenyl)tetrahydrofuran,2-(3,4-Methylenedioxybenzyl)-3-(3-methoxy-4-hydroxyphenyl)-1,4-butanediol(5),2R,3S,4S-2-Hydroxy-3,4-di-(3,4-Methylenedioxybenzyl)tetrahydrofuran(6)respectively.Conclusion:Compounds 1,2,3 and 5 are separated from akaru initially,compounds 4 and 6 from the plant stem and roots for the first time.