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宫腔镜电切术联合孕激素对早期子宫内膜癌患者临床疗效以对生育功能的影响分析 被引量:9

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摘要 目的探讨宫腔镜电切术联合孕激素对早期子宫内膜癌患者疗效及生育功能的影响。方法 50例早期子宫内膜癌患者,随机分为研究组和对照组,每组25例。对照组仅予以宫腔镜电切术治疗,研究组在对照组基础上于术后1周于宫腔内置入左炔诺孕酮宫内节育系统。比较两组患者的复发、受孕成功情况及术前术后糖链抗原(CA125)水平。结果随访2年,研究组出现2例复发,复发率为8%;对照组出现3例复发,复发率为12%,比较差异无统计学意义(X^2=0.222, P>0.05);研究组受孕成功率为84%,明显高于对照组的52%,差异具有统计学意义(X^2=5.882, P<0.05)。术前,两组患者的CA125水平比较差异无统计学意义(P>0.05)。术后,两组患者的CA125水平均显著低于术前,差异具有统计学意义(P<0.01);且研究组患者术后的CA125(21.07±2.65)U/ml低于对照组的(28.79±3.01)U/ml,差异具有统计学意义(t=9.625, P<0.01)。结论宫腔镜电切术联合孕激素可有效提升早期子宫内膜癌患者临床表现,有效控制病情进展,降低复发率及提升受孕成功率,值得临床推广应用。
作者 徐宏甲 张洁
出处 《中国现代药物应用》 2019年第5期113-114,共2页 Chinese Journal of Modern Drug Application
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