微创保胆取石术后患者胆囊功能恢复情况的影响因素分析

Analysis of factors influencing the recovery of gallbladder function in patients after minimally invasive gallbladder-protected lithotomy

目的探讨微创保胆取石术后患者胆囊功能恢复情况的影响因素。方法回顾性分析2015年4月至2016年11月我院144例微创保胆取石术患者相关资料,目标性监测术后胆囊功能恢复异常患者。引入logistic逐步回归分析微创保胆取石术后胆囊功能恢复异常的影响因素。结果 144例微创保胆取石术后胆囊功能恢复正常109例(75. 69%),胆囊功能恢复异常35例(24. 31%)。不同性别(女)、年龄(≥50岁)、体重(≥70 kg)、结石数目(多发)、术前症状、胆囊壁厚度(≥0. 3 cm)、糖尿病、胆囊炎症患者术后胆囊功能恢复情况比较差异有统计学意义(P <0. 05)。引入logistic逐步回归分析显示,性别、年龄、结石数目、术前症状、胆囊壁厚度、糖尿病、胆囊炎症、三酰甘油、胆固醇是微创保胆取石术后胆囊功能恢复异常的危险因素,差异有统计学意义(P <0. 05)。结论微创保胆取石术后患者胆囊功能恢复影响因素众多,如性别、年龄、结石数目、术前症状、三酰甘油、胆固醇等,及时准确掌握上述因素,利于早期采用相应防控措施,促进术后胆囊功能恢复,降低结石复发率。

Objective To explore the factors influencing the recovery of gallbladder function in patients after minimally invasive gallbladder-protected lithotomy. Methods To analyze the data of 144 patients with minimally invasive gallbladder-protected lithotomy in our hospital from April 2015 to November 2016 by retrospective analysis. Patients with abnormal gallbladder function recovery were monitored. Logistic stepwise regression analysis was introduced to analyze the influencing factors of abnormal gallbladder function recovery after minimally invasive gallstone removal. Results Of the 144 patients with minimally invasive gallstones surgery, 109 patients(75.69%) had recovered normal gallbladder function and 35 patients(24.31%) had abnormal gallbladder function recovery. There were significant statistical differences in the recovery of gallbladder function between patients of different genders (female), age(≥50 years old), weight(≥70 kg), number of stones (multiple), preoperative symptoms, gallbladder wall thickness(≥0.3 cm), diabetes, and gallbladder inflammation( P <0.05). The introduction of logistic stepwise regression analysis showed that genders, age, number of stones, preoperative symptoms, gallbladder wall thickness, diabetes, gallbladder inflammation, triglyceride and cholesterol were risk factors for abnormal gallbladder function recovery after minimally invasive gallstone removal,and the difference was statistically significant( P <0.05). Conclusion There are many factors influencing the recovery of gallbladder function after minimally invasive gallstone removal, such as gender, age, number of stones, preoperative symptoms, triglycerides, cholesterol, etc. To grasp the above factors timely and accurately is conducive to the early adoption of appropriate prevention and control measures. Meanwhile, it can promote postoperative gallbladder function recovery and reduce the rate of calculus recurrence.