呼吸操及肌力训练联合布地奈德吸入治疗对COPD患者预后及生活质量的影响

Effects of respiratory exercise and muscle strength training combined with budesonide inhalation on prognosis and quality of life in patients with COPD

目的探讨呼吸操及肌力训练联合布地奈德吸入治疗对慢性阻塞性肺疾病(COPD)患者预后及生活质量的影响。方法选取2014年3月至2017年8月COPD患者186例,将患者随机等分为观察组和对照组。对照组采用布地奈德混悬液2 ml+生理盐水1 ml经氧驱动雾化吸入,观察组在此基础上加用呼吸操及呼吸肌力训练,比较两组患者治疗前后临床症状、肺功能、运动耐力和生活质量评分。结果观察组患者治疗后呼吸困难评分低于对照组(P <0. 05),观察组FVC、FEV1、FEV1/FVC、FEV1、PEF和6 min步行距离优于对照组(P <0. 05),呼吸症状、活动能力受限、日常生活受疾病影响评分低于对照组(P <0. 05)。结论呼吸操及肌力训练联合布地奈德吸入治疗COPD效果显著,能有效改善患者生活质量,尤其呼吸操更符合我国国情,患者易于接受,依从性良好,值得临床推广应用。

Objective To investigate the effect of respiratory exercise and muscle strength training combined with budesonide inhalation on prognosis and quality of life in patients with chronic obstructive pulmonary disease (COPD). Methods To select 186 cases of patients with COPD in the hospital from March 2014 to August 2017, and they were divided into observation group and control group with the same number of patients randomly. The control group was treated with 2 ml of budesonide suspension and 1 ml of saline via oxygen-driven aerosol inhalation. On this basis, the observation group was treated with respiratory exercise combined with muscle strength training. The clinical symptoms, lung function, exercise endurance and quality of life scores of the two groups were compared before and after the treatment. Results After treatment,the dyspnea scores of the observation group were lower than those of the control group( P <0.05). The FVC,FEV 1,FEV 1/FVC,FEV 1,PEF and 6 min walking distance of the observation group were better than that of the control group( P <0.05). The respiratory symptoms, activity ability limitation, and scores of daily life affected by the disease in the observation group were lower than that of the control group( P <0.05). Conclusion Respiratory exercise and muscle strength training combined with budesonide inhalation for patients with COPD is effective, which can improve the quality of life of patients effectively. In particular, breathing exercise is more in line with China's national conditions. Patients are easy to accept this kind of exercise, and the compliance is good,which was worthy of clinical promotion and application.