不同药物组合雾化吸入治疗小儿喘息性支气管炎的临床观察

Clinical observation of nebulized inhalation of different drugs in the treatment of asthmatic bronchitis in children

目的分析不同药物组合雾化吸入治疗小儿喘息性支气管炎的临床效果。方法选择2016年1月至2017年12月在本院接受治疗的喘息性支气管炎59例作为研究对象,按照随机原则结合意愿将其分成对照组(n=27)及观察组(n=32);对照组采取布地奈德、特布他林雾化吸入,观察组联用布地奈德、异丙托溴铵以及特布他林雾化吸入进行治疗,分析两组治疗效果差异。结果观察组治疗总有效率96.88%(31/32)显著高于对照组77.78%(21/27)(P<0.05);观察组症状消失时间均显著短于对照组(P<0.05);观察组治疗7 d后PTEF、ME/MI均显著低于对照组及治疗前(P<0.05)。结论联用孟鲁司特、布地奈德、异丙托溴铵以及特布他林雾化吸入治疗小儿喘息性支气管炎的临床效果较好。

Objective To analyze the clinical effects of aerosol inhalation in the treatment of children with asthmatic bronchitis. Methods A total of 59 patients with asthmatic bronchitis who were treated in our hospital from January 2016 to December 2017 were enrolled. According to the random principle, they were divided into control group (n=27) and observation group (n=32). The control group was treated with budesonide and terbutaline, and the observation group was treated with budesonide, ipratropium bromide and terbutaline inhalation. The difference of treatment effects between the two groups was analyzed. Results The total effective rate of the observation group was 96.88%(31/32), which was significantly higher than that of the control group 77.78%,(21/27)(P<0.05). The disappearance time of the observation group was significantly shorter than that of the control group (P<0.05). After 7 days of treatment, PTEF and ME/MI were significantly lower than those in the control group and before treatment (P<0.05). Conclusion The clinical efficacy of inhalation of montelukast, budesonide, ipratropium bromide and terbutaline in the treatment of children with asthmatic bronchitis is better.