米索前列醇直肠用药联合缩宫素对剖宫产术后出血的预防效果

Preventive effect of Misoprostol rectal medication combined with Oxytocin on hemorrhage after cesarean section

目的探讨米索前列醇直肠用药联合缩宫素对剖宫产术后出血的预防效果。方法选取2018年1～6月于我院行剖宫产手术的80例产妇作为研究对象,随机分为对照组和观察组,每组各40例。两组产妇均在胎儿娩出后立即给药,对照组产妇接受宫体注射缩宫素,观察组产妇在胎儿娩出后除宫体注射缩宫素给予肛塞米索前列醇治疗。观察并比较两组产妇术中及产后24 h的出血量,产前、产后血红蛋白水平及不良反应发生情况。结果两组产妇术中及术后24 h出血量比较,差异无统计学意义(P>0.05)。两组产妇产前和产后血红蛋白水平比较,差异无统计学意义(P>0.05)。两组产妇均无不良反应发生。结论直肠用米索前列醇片联合缩宫素与单纯使用缩宫素对预防产后出血没有差异,临床应根据具体情况选择用药。

Objective To explore the preventive effect of Misoprostol rectal medication combined with Oxytocin on hemorrhage after cesarean section.Methods Eighty parturients who underwent caesarean section in our hospital from January to June 2018 were randomly divided into control group and observation group,with 40 cases in each group.Both groups were given Oxytocin immediately after the delivery of the fetus,the control group received Oxytocin injection into the uterus,the observation group was given anal misoprostol after the delivery of the fetus.Observe and compare the amount of bleeding during and 24 hours after delivery,the level of hemoglobin before and after delivery and the occurrence of adverse reactions between the two groups.Results There was no significant difference in the amount of bleeding during operation and 24 hours after operation between the two groups(P>0.05).There was no significant difference in prenatal and postpartum hemoglobin levels between the two groups(P>0.05).There were no adverse reactions in both groups.Conclusion There is no difference between rectal Misoprostol Tablets combined with Oxytocin and simple use of Oxytocin in preventing postpartum hemorrhage.