一种高效快捷的肛肠外科给药装置临床应用效果及评价分析

Analysis on the clinical effect and evaluation for an efficient and rapid drug-delivery device of anus and intestine surgery

目的:分析自制的一种高效快捷肛肠外科给药装置的临床应用效果和评价情况。方法:分析医院收治的110例肛肠疾病患者临床资料,按照使用高效快捷肛肠外科的给药装置与否将其分为观察组和对照组,每组55例,观察组使用给药装置,对照组未使用给药装置,对两组临床效果、交叉感染发生概率进行观察和比较,按视觉模拟量表(VAS)评分法对患者疼痛情况加以评判,采用美国波士顿健康研究所的生活质量简式-36(SF-36)健康量表对患者生活质量予以评判。结果:观察组创面水肿消退时间、创面愈合时间、创面渗出物和疼痛的消失时间均较短,与对照组比较差异均有统计学意义(t=6.2359,t=13.5394,t=17.0297,t=6.3502;P<0.05);观察组交叉感染发生概率为1.82%,较对照组低,且重度、中度疼痛所占比例分别为0.00%和14.55%,均比对照组低,其差异有统计学意义(x^2=16.0417,x^2=6.8990;P<0.05),无疼痛所占比例30.91%,均比对照组高,其差异有统计学意义(x^2=20.1075,P<0.05);所有病例进行半年随访,观察组生活质量总评分(83.54±14.49)分,比对照组(65.40±13.31)分高,其差异有统计学意义(t=6.8375,P<0.05)。结论:应用一种高效快捷肛肠外科的给药装置可加速患者创面愈合,减轻疼痛和减少交叉感染发生,且提高患者生活质量,具有较高临床应用意义。

Objective: To analyze the clinical effect and evaluation of an efficient and rapid drug-delivery device of anus and intestine surgery. Methods: The clinical data of a total of 110 patients with anorectal disease were analyzed and all of them were divided into observation group(55 cases) and control group(55 cases) according to whether adopted drug-delivery device. The observation group adopted drug-delivery device and control group didn’t adopted this device. The clinical effect and cross infection rate of the two groups were observed and compared. The pain feel of patients were assessed as visual analogue scale and the quality of life(QOL) of patients were assessed as simple formula(SF-36) of living quality of Boston institute for health of USA. Results: The times for edema regression and wound healing, the extinction times of transudation and pain of the surface of wound in the observation group were significantly shorter than those in the control group(t=6.2359, t=13.5394, t=17.0297, t=6.3502, P<0.05). The crossinfection rate of observation group(1.82%) was significantly lower than that(18.18%) of control group(x^2=8.1818, P<0.05). And the rates of severe pain and moderate pain of observation group(0.00% and 14.55%) were significantly lower than those of control group(x^2=16.0417, x^2=6.8990, P<0.05). And the rate of non-pain of observation group(30.91%) was significantly higher than that of control group(x^2=20.1075, P<0.05). After half-year, the results of follow-up for all of patients indicated the total score of QOL of observation group(83.54±14.49 points) was significantly higher than that(65.40±13.31 points) of control group(t=6.8375, P<0.05). Conclusion: The application of an efficient and rapid drug-delivery device of anus and intestine surgery can contribute to accelerate wound healing of patients, and alleviate pain and reduce the occurrence of cross-infection, and improve the patients’ QOL. Therefore, it has higher value in popularization and application.