双黄连口服液与雷尼替丁治疗口腔溃疡的临床观察

Clinical observation of Shuanghuanglian Oral liquid and ranitidine in the treatment of Oral ulcer

目的探究双黄连口服液与雷尼替丁治疗口腔溃疡的临床疗效。方法对120例口腔溃疡患者进行分析,随机分为对照组60例(采用雷尼替丁与维生素治疗)与实验组60例(采用雷尼替丁联合双黄连口服液治疗),对比两组治疗效果。结果在治疗总有效率对比中,实验组(95.0%)与对照组(78.3%)比较,差异有统计学意义(P<0.05)。两组患者治疗后的WBC计数、LYN计数、IgG与SIgA水平与治疗前比较,差异显著;治疗后实验组的WBC计数、LYN计数、IgG与SIgA水平均明显优于对照组,差异有统计学意义(P<0.05)。实验组患者复发率为3.3%(2/60),对照组复发率为18.3%(11/60),比较差异有统计学意义(P<0.05)。结论在口腔溃疡患者中采用雷尼替丁与双黄连口服液治疗,可以取得较好的治疗效果,能够促使溃疡快速愈合,改善患者的临床症状,具有较高的临床应用价值。

Objective To explore the clinical efficacy of shuanghuanglian oral liquid and ranitidine in the treatment of oral ulcer. Methods 120 patients with oral ulcer were analyzed and randomly divided into the control group (60 cases treated with ranitidine and vitamin) and the experimental group (60 cases treated with ranitidine combined with shuanghuanglian oral liquid) to compare the therapeutic effects of the two groups. Results In the comparison of the total effective rate of treatment, the difference between the experimental group (95.0%) and the control group (78.3%) was statistically significant (P<0.05). WBC count, LYN count, IgG and SIgA levels of patients in the two groups after treatment were significantly different from those before treatment. After treatment, WBC count, LYN count, IgG and SIgA levels in the experimental group were significantly better than those in the control group (P<0.05). The recurrence rate of patients in the experimental group was 3.3%(2/60), and that of the control group was 18.3%(11/60). The difference was significant and statistically significant (P<0.05). Conclusion In patients with oral ulcer, the use of ranitidine and shuanghuanglian oral liquid treatment, can achieve better therapeutic effect, can promote the rapid healing of ulcer, improve the clinical symptoms of patients, has a high clinical application value.