深部浸润型子宫内膜异位症相关肠道功能紊乱的研究进展

Progress of Intestinal Dysfunction Associated with Deep Infiltrating Endometriosis

深部浸润型子宫内膜异位症(deeply infiltrating endometriosis,DIE)是子宫内膜异位症(endometriosis,EMs)最严重的类型,其伴随的周期性的排便痛、便血、肠绞痛、腹泻腹胀,甚至肠梗阻等肠道症状严重影响患者的生活和工作质量,但临床重视不足。目前,手术仍然是有症状的DIE患者首选的治疗方式,但关于手术对患者肠道症状的改善程度以及术后新发的肠道功能紊乱尚没有明确的临床研究。影响患者术后肠道功能恢复的因素有很多,因此术前需通过多种方法详细评估其肠道功能,联合多学科协同制定治疗方案,并在术后进一步探讨可能改善肠道功能的方法,从而改善患者肠道症状,促进其全面康复。

Deeply infiltrating endometriosis(DIE) is the most serious type of endometriosis (EMs). It related with intestinal dysfunction, such as cyclical defecation pain and hematochezia, intestinal cramping, diarrhea, bloating, even intestinal stenosis, which seriously affects the quality of life of patients. Yet these symptoms are often omitted in current clinical practice. Surgery is still the first choice for symptomatic patients. However, the improvement of intestinal symptoms after surgery and postoperative intestinal dysfunction are not clear. There are many factors affecting the recovery of intestinal function. Therefore, it is necessary to evaluate intestinal function in detail by various methods and formulate treatment regimen by multidisciplinary cooperation, then further explore possible ways to improve intestinal function. Ultimately, we hope to improve the symptoms and promote the comprehensive recovery of patients.