2015～2017年浙江省台州医院门诊口服镇静催眠药的临床应用分析

Analysis on the clinical application of oral sedative and hypnotic drugs in the outpatient clinic in Zhejiang Taizhou Hospital from 2015 to 2017

目的了解2015～2017年我院门诊口服镇静催眠药的使用情况及变化规律,为临床合理用药提供参考。方法根据从门诊西药房管理信息系统中搜索的数据材料,回顾性统计分析3年内口服镇静催眠药的销售金额、用药频度(DDDs)、日均费用(DDC)和排序比(B/A)等情况。结果 3年内我院口服镇静催眠药的销售金额年增长率分别为60.33%和52.46%;奥沙西泮在引进之后迅速得到临床的青睐,DDDs值成倍增长,排名上升到第4位;这3年奥沙西泮的DDC值相对最高且几无变化,表示该药的每日消耗费用的一直处于高水平状态,提示临床医生不要将其做为失眠的首选药。唑吡坦作为一种新型镇静催眠药其排序比(B/A)在逐渐接近1,同步性越来越好,满足患者的需要。结论临床医师应当合理选择药物,使患者的经济效益和社会效益得到满足。

Objective To understand the use and principle of changes of oral sedative and hypnotic drugs in the outpatient clinic in our hospital from 2015 to 2017, so as to provide references for clinical rational drug use. Methods According to the data and materials retrieved from the outpatient western pharmacy management information system, the total amount of sales, defined daily doses (DDDs), defined daily cost (DDC), and sorting ratio (B/A) of oral sedative and hypnotic drugs within 3 years were retrospectively analyzed. Results The annual growth rates of the amount of sales of oral sedative and hypnotic drugs in our hospital in the past 3 years were 60.33% and 52.46%, respectively;oxazepam quickly gained clinical favor after its introduction. The value of DDDs was doubled, and its ranking was increased to the 4th place;the DDC value of oxazepam in the past 3 years was relatively highest and was not changed, indicating that the daily consumption cost of the drug had been at a high level. This suggested that clinicians not use it as the drug of choice for insomnia. As a new type of sedative and hypnotic drug, the B/A of zolpidem was gradually approaching 1, and the synchronism was getting better and better, which met the needs of patients. Conclusion Clinicians should rationally choose drugs to meet the economic and social benefits of patients.