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瑞舒伐他汀治疗冠心病并发2型糖尿病患者的疗效分析 被引量:1

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摘要 目的:探讨瑞舒伐他汀治疗冠心病并发2型糖尿病患者的疗效。方法:纳入本院2017年2月—2018年4月收治的100例冠心病并发2型糖尿病患者。按随机数表法分为对照组(50例)和观察组(50例),对照组患者给予强化降糖、抗血小板、抗心机缺血、调整饮食等常规治疗,观察组患者在对照组治疗的基础上加用瑞舒伐他汀口服,20 mg/d。两组均连续治疗3个月。比较两组临床疗效、同级别心功能好转时间、血糖达标时间、治疗前后空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、低密度脂蛋白胆固醇(LDL-C)、超敏C反应蛋白(hs-CRP)改善情况;比较两组治疗后心绞痛及再发心肌梗死的发生率。结果:观察组治疗总有效率为98%,显著高于对照组的80%(P <0. 05);观察组同级别心功能好转时间、血糖达标时间均显著低于对照组(P <0. 05);观察组治疗后FBG、2 h PBG、LDL-C、hs-CRP均明显低于对照组(P <0. 05);观察组治疗后心绞痛及再发心肌梗死的发生率均明显低于对照组(P <0. 05)。结论:瑞舒伐他汀治疗冠心病并发2型糖尿病的疗效确切,可有效降低血脂水平,改善患者心肌功能,减少心血管不良事件的发生,值得应用。
作者 赵建成
出处 《天津药学》 2019年第1期23-25,共3页 Tianjin Pharmacy
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