中孕期胎儿超声软指标对筛查21-三体综合征的临床价值

Clinical Value of Ultrasound Soft Index in Screening 21-trisomy Syndrome during Middle Pregnancy

目的:探讨超声软指标在中孕期胎儿21-三体综合征诊断中的临床价值。方法:对2013年2月～2015年3月来某院进行产前筛查的2127例孕妇进行超声检查,分析超声软指标、胎儿结构畸形或其他异常情况与21-三体综合征的关系。结果:共筛查出超声1项软指标异常率12.4%,2项软指标异常者2.1%,3项软指标异常率0.3%,比较3项软指标异常率,P<0.05。结论:在中孕期胎儿的结构发育检查中,21-三体综合征胎儿通常会出现软指标与结构畸形或其他异常情况,以及多个超声软指标共同出现的临床征象,可作为临床诊断的依据。

Objective:To explore the clinical value of ultrasound soft index in the diagnosis of 21-trisomy syndrome during middle pregnancy.Methods:2127 pregnant women who underwent antenatal screening in a hospital from February 2013 to March 2015 were examined by ultrasound,and the relationship between ultrasound soft index,fetal structural malformation or other abnormalities and trisomy 21 syndrome was analyzed.Results:The abnormal rate of 1,2 and 3 soft index of ultrasound was 12.4%,2.1%and 0.3%respectively,compared the abnormal rates of 3 soft indexes,P<0.05.Conclusion:In the examination of fetal structure development during the middle pregnancy,21-trisomy syndrome fetuses usually appear soft index and structural deformity or other abnormal situation,as well as a number of clinical signs of multiple soft ultrasound indicators,which can be used as the basis of clinical diagnosis.