有氧运动预干预对睡眠剥夺大鼠心肌凋亡因子的研究

探讨8周有氧运动预干预对部分睡眠剥夺大鼠心肌NF-κB介导凋亡相关因子水平的研究。6周龄SD大鼠分为安静对照组(CC)、运动组(EX)、睡眠剥夺组(SD)、运动预干预睡眠剥夺组(ES)。EX和ES组进行8周有氧运动后,ES组和SD组进行14d部分睡眠剥夺,检测心肌组织TNF-αmRNA表达水平,心肌NF-κB、FAS、FAS-L、Caspase-3蛋白表达水平。结果显示8周有氧运动预干预可能降低心肌凋亡促进因子的表达水平。

To investigate the effects of 8-week aerobic exercise on the levels of NF-κB related factors in myocardium of rats with partial sleep deprivation. Six week-old SD rats were divided into four groups: control group (CC), exercise group(EX),sleep deprivation group(SD),and exercise preintervention sleep deprivation group(ES).The results showed that 8-week aerobic exercise pre-intervention may reduce the expression level of myocardial apoptosis promoting factor.