加味麻黄附子细辛汤辅助布地奈德治疗老年支气管哮喘寒哮证的疗效及对肺功能的影响临床观察

Efficacy of the Mahuang Fuzi Xixin decoction plus budesonide on elderly bronchial asthma of the Hanxiao syndrome and lung function

目的:对加味麻黄附子细辛汤辅助布地奈德治疗老年支气管哮喘寒哮证的疗效及其对肺功能的影响进行临床观察。方法:将2016年12月-2017年12月到我院接受治疗的40例老年支气管哮喘寒哮证患者随机分为观察组和对照组各20例。对照组患者接受的是常规疗法配合布地奈德气雾剂开展治疗,观察组患者在对照组的基础上加用加味麻黄附子细辛汤治疗。治疗结束后对两组患者的有关症状体征、肺功能、不良反应等进行对比与分析。结果:观察组的治疗总有效率为95.0%,明显高于对照组的75.0%(P <0.05);将两组患者接受治疗前后的状态进行比较,发现其ACT评分在治疗后都得到了明显的提高(P <0.05),观察组ACT评分的提升明显高于对照组(P <0.05);两组患者治疗后FEV_1和PEF都得到了提高,观察患者治疗后的FEV_1和PEF高于对照组(P <0.05);两组患者治疗后的IgE和EOS指数降低(P <0.05),观察组患者的IgE和EOS指数较对照组降低得更多(P <0.05)。结论:加味麻黄附子细辛汤辅助布地奈德治疗老年支气管哮喘寒哮证疗效显著,能够有效改善患者各类症状,增强患者的肺功能。

Objective: To observe clinical efficacy of the Mahuang Fuzi Xixin decoction (麻黄附子细辛汤) plus budesonide on elderly bronchial asthma of the Hanxiao syndrome (寒哮证) and lung function. Methods: 40 cases were divided into two groups, 20 cases in each. The control group was given conventional treatment plus budesonide aerosol;and the observation group was given the Mahuang Fuzi Xixin decoction more. Results: The total efficiency was 95.0% in the observation group, higher than 75% in the control group, P<0.05. After treatment, the ACT scores, FEV1 and PEF in two groups were significantly increased (P<0.05);and those in the observation group were higher than the control group (P<0.05). IgE and EOS indices were lower in both groups (P<0.05);and those in the observation group were better (P<0.05). Conclusion: The Mahuang Fuzi Xixin decoction plus budesonide on elderly bronchial asthma of the Hanxiao syndrome shows a good effect, can improve clinical symptoms and lung function.