幽门螺旋杆菌与痤疮及其中医分型的关系研究

An analysis of relationship between Helicobacter pylori and acne with its TCM syndrome type

目的:探讨幽门螺旋杆菌与痤疮以及痤疮中医分型的关系。方法:将研究对象分为痤疮组120例和健康对照组40例,其中痤疮组分为风热证组40例、痤疮湿热证组40例、痤疮血瘀或痰凝证组40例,通过14C呼吸试验及胶体金法测定研究对象幽门螺旋杆菌,通过χ2检验分析其与痤疮及其中医分型的关系。结果:痤疮组患者螺旋杆菌抗体阳性率显著高于健康对照组(χ2=11.555,P=0.001)。在痤疮组中,湿热证组的阳性率要显著高于其他组(χ2=7.823,P=0.020),湿热证组有胃部症状阳性率要显著高于其他证组(χ2=6.382,P=0.041)。结论:幽门螺旋杆菌在痤疮的发病可能起着一定的作用,不同中医证型的幽门螺旋杆菌检测率不同。

Objective: To investigate relationship between Helicobacter pylori and acne and its TCM syndrome type. Methods: All patients were divided into the acne group (120 cases) and the control group (40 cases). Helicobacter pylori was measured by 14C breath test and colloidal gold method. The relationship between Helicobacter pylori and acne and its TCM classification was analyzed by χ^2. Results: The positive rate of the Helicobacter antibody in the acne group was significantly higher than that in the control group (χ^2=11.555, P=0.001). In the acne group, the positive rate of the Shire syndrome (湿热证) group was the highest (χ^2=7.823, P=0.020), and the positive rate of gastric symptoms was the highest (χ^2=6.382, P=0.041). Conclusion: Helicobacter pylori may be one of the causes of acne, and the detection rates of Hp in different TCM syndromes are different.