补中益气汤加味联合舒利迭治疗慢性阻塞性肺疾病的临床疗效

Clinical efficacy of the Buzhong Yiqi decoction plus seretide on COPD

目的:探究慢性阻塞性肺疾病(慢阻肺)患者实施补中益气汤联合舒利迭治疗的效果。方法:研究以2015年10月-2016年10月在鹤山市中医院内一科收集的慢阻肺急性加重期患者共40例作为实验对象,根据患者入院先后顺序将其分为对照组与治疗组,每组20例。对照组实施常规治疗联合舒利迭治疗,治疗组基于对照组疗法实施补中益气汤治疗,记录并比较两组患者临床疗效及中医证候积分。同时在治疗前后为患者实施呼吸困难指数(mMRC)、BODE指数、慢阻肺评估测试量表(CAT)测试,并记录相应分值,同时检测患者治疗前后炎症因子水平。结果:治疗前两组患者中医证候总积分、BODE指数、mMRC指数以及CAT评分及炎症因子经比较差异均无统计学意义(P> 0.05),治疗后治疗组患者IL-10显著高于对照组,且中医证候总积分、BODE指数、mMRC指数、CAT评分、IL-17及IL-23则显著低于对照组,数据对比差异有统计学意义(P <0.05)。结论:慢阻肺患者实施补中益气汤联合舒利迭治疗具有确切疗效,值得在临床中针对该种治疗方案进行推广。

Objective: To investigate clinical efficacy of the Buzhong Yiqi decoction (补中益气汤) plus seretide on Chronic Obstructive Pulmonary Disease. Methods: From October 2015 to October 2016, 40 cases were divided into two groups, 20 cases in each. The control group was given conventional treatment plus seretide;and the treatment group was given the Buzhong Yiqi decoction more. Results: After treatment, the clinical efficacy and inflammatory factors in the treatment group were significantly higher than the control group, and the TCM syndrome total score, BODE index, mMRC index, CAT score, IL-17 and IL-23 were significantly lower than the control group (P<0.05). Conclusion: The Buzhong Yiqi decoction plus seretide on COPD shows a good effect, and is worthy of promotion.