2型糖尿病血瘀证与凝血功能的相关性研究

Correlation between blood stasis and coagulation function in type 2 diabetes mellitus

目的:研究2型糖尿病血瘀证与凝血功能的相关性,统计2型糖尿病血瘀证患者发生糖尿病并发症的发生率。方法:纳入2型糖尿病患者107例,其中血瘀证组58例,非血瘀证组49例,比较两组患者的一般资料、凝血功能及糖尿病视网膜病变、糖尿病肾脏病变、糖尿病周围神经病变的发生率。结果:2型糖尿病患者血瘀证组相较于非血瘀证组,年龄更大,病程更长,凝血系列的APTT、Fb、AT3和D-二聚体均有明显差异,经相关性检验,发现2型糖尿病血瘀证与APTT、Fb、AT3有显著相关性,经卡方检验,2型糖尿病血瘀证患者较非血瘀证患者发生并发症的概率也更高。

Objective: To study the correlation between blood stasis syndrome and coagulation function of type 2 diabetes mellitus and to calculate the incidence of diabetes complications in type 2 diabetic patients with blood stasis syndrome. Methods: A total of 107 cases of type 2 diabetes were included, including 58 cases in the blood stasis syndrome group and 49 cases in the non-blood stasis syndrome group. The general data, coagulation function and the incidence of diabetic retinopathy, diabetic nephropathy and diabetic peripheral neuropathy were compared between the two groups. Results: Patients with type 2 diabetes and blood stasis syndrome group were older, suffered from longer duration, had had more significant difference in the blood coagulation series of APTT, Fb, AT3 and D-Dimer the correlation test found that type 2 diabetes were significantly correlated with blood stasis and APTT, Fb, AT3, chi-square test showed that type 2 diabetes patients had higher probability of complications in blood stasis syndrome patients.