单纯自身抗体异常的桥本甲状腺炎中医治疗进展

The Progress of TCM treatment of Hashimoto's thyroiditis with abnormal autoantibodies

桥本甲状腺炎(HT)是目前尚无法治愈的自身免疫性疾病,以血清中存在高滴度的过氧化物酶抗体(TPOAb)和甲状腺球蛋白抗体(TGAb)为主要特征,可引起甲状腺功能减退。在甲状腺功能正常期,降低高滴度的甲状腺自身免疫性抗体,对于阻止或延缓HT进展、改善患者预后至关重要。本文从中药内服(包括单药和复方)、外治等方面对甲功正常、单纯自身抗体升高的HT的中医药研究进展进行综述,同时也对育龄期女性的中医药治疗进行总结。结论:中医药在改善症状、降低甲状腺自身抗体等方面具有明显优势,为正常甲状腺功能的HT的治疗提供临床参考,坚定了我们运用中医药治愈HT的信心。

Hashimoto’s Thyroiditis (HT) is an autoimmune disease that can not be completely cured. High level of thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TGAb) in the serum are its main features. HT can cause hypothyroidism. During the thyroid function normal period, it is very important to reduce the level of autoimmune antibodies of the thyroid gland, so as to prevent or delay the progression of HT and improve the prognosis of patients. This paper reviews the progress of traditional Chinese medicine(TCM) treatment in HT patients with normal thyriod function and high level of thyroid autoimmune antibodies. Also, the paper summarizes oral, including single and compound traditional Chinese herb, and external using herbs. Moreover, the TCM treatment also benefits reproductiveage women with HT. Conclusion: TCM treatment can significantly relieve the clinical symptoms and improve antibody levels in patient with HT. It provides a clinical reference for the treatment of HT with normal thyriod function and also strengthens our determination to cure HT with traditional Chinese medicine.