达克罗宁胶浆对食道闭锁术后食道扩张术患者苏醒质量的影响

Influence of Dyclonine Mucilagines on Awakening Quality in Children Undergoing Bougienage for Esophageal Atresia

目的探讨达克罗宁胶浆用于食道闭锁术后食道扩张术手术中对患者苏醒质量的影响。方法食道闭锁术后行食道扩张术患儿60例,按简单随机方法分为达克罗宁组(A组)和对照组(B组),每组30例。所有患儿均采取全凭静脉麻醉,开始在胃镜辅助下行探条扩张。术前,A组在胃镜及探条表面涂抹达克罗宁胶浆,B组涂普通石蜡润滑油。分别记录术前5 min(T_1)、术中5 min(T_2)、术后15min(T_3)3个时间点的心率(HR)、平均动脉压(MAP);记录2组患儿术中出现的体动或术后出现的呛咳、呕吐、躁动等不良反应例数。结果各临床监测时间点MAP、HR组间比较差异无统计学意义(均P>0.05);A组术中出现的体动或术后出现的呛咳、呕吐、躁动等不良反应发生率明显低于B组(P<0.05)。结论达克罗宁胶浆术中涂抹在胃镜及探条表面,可以降低患儿苏醒期不良反应发生率,提高手术苏醒质量和患儿耐受手术的舒适度。

Objective To explore the influence of dyclonine mucilagines on awakening quality in children undergoing bougienage for esophageal atresia.Methods Sixty children with esophageal atresia receiving total intravenous anesthesia for gastroscope-assistant bougienage were randomly divided into two groups,with 30 children in each group.Before operation,the surfaces of gastroscope tube and bougie were smeared with dyclonine mucilagines and liquid paraffin in group A and group B,respectively.The heart rate(HR),mean arterial pressure(MAP)were measured at 5 minutes before operation(T 1),5 minutes after the start of operation(T 2),and 15 minutes after operation(T 3).Intraoperative body movement and postoperative coughing,vomiting and agitation were recorded in both groups.Results There were no significant differences in HR and MAP between the two groups(P>0.05).The incidences of intraoperative body movement and postoperative coughing,vomiting and agitation in group A were lower than those in group B(P<0.05).Conclusion The application of dyclonine mucilagines on the surfaces of gastroscope tube and bougie can reduce the incidence of adverse reaction,improve the quality of recovery and increase the degree of comfort in children undergoing gastroscope-assistant bougienage.