Trousseau综合征的研究进展

Research Progressin Trousseau Syndrome

文章从发病机制、临床表现、诊断方法和治疗四方面对Trousseau综合征进行整理概述。Trousseau综合征是一类主要以机体凝血与纤溶机制异常引起机体血栓栓塞等为主要发病机制的综合征,临床多表现为肢体栓塞、内脏栓塞和血栓性静脉炎等,血液学和影像学检查大多可诊断,积极的抗凝治疗与原发肿瘤治疗是本病的治疗关键。临床上对难以解释的血栓或高凝症状,可考虑进行相关肿瘤的预防性筛查,减少漏诊和误诊,并进行针对性治疗,以改善患者的预后。

The purpose of this article is to organize and summarize the pathogenesis,clinical manifestations,diagnostic methods and treatment of Trousseau syndrome,a type of syndrome mainly characterised by thrombosis and embolism and caused by abnormal blood coagulation and fibrinolysis.The clinical manifestations of Trousseau syndrome include limb embolism,visceral embolism and thrombophlebitis.Most of them can be diagnosed by hematology and imaging examination.Active anticoagulation and primary tumortherapyare the keys to the treatment of this disease.For unexplained thrombosis or hypercoagulable symptoms,preventive tumor screening can be considered to reduce the missed diagnosis and misdiagnosis.In addition,targeted treatmentshould be performed to improve the prognosis of patients.