2Selvin E,Coresh J,Brancati FL.The burden and treatment of diabetes in elderly individuals in the US[J].Diabetes Care,2006,29:2415-2419.
3Yang W,Lu J,Weng J,et al.Prevalence of diabetes among men and woman in China[J].N EngI J Med,2010,362:1090-1101.
4Sinclair AJ,Robert IM,Croxson SCM.Mortality in older people with diabetes mellitus[J].Diabet Med,1996,14:639-647.
5Pratley RE,Rosenstock J,Pi-Sunyer FX,et al.Management of type 2 diabetes in treatment-naive elderly patients:benefits and risks of vildagliptin monotherapy[J].Diabetes Care,2007,30:3017-3022.
6Araki A,Iimuro S,Sakurai T,et al.Japanese Elderly Diabetes Intervention Trial Study Group.Long-term multiple risk factor interventions in Japanese elderly diabetic patients:the Japanese Elderly Diabetes Intervention Trial Study design,baseline characteristics,and effects of intervention[J].Geriatr Gerontol Int,2012,12 (Suppl 1):7-17.
7American Diabetes Association.Standards of Medical Care in Diabetes-2010[J].Diabetes Care,2010,33 (Suppl 1):S11-S61.
8Li CL,Pan CY,Lu JM,et al.Effect of metformin on patients with impaired glucose tolerance[J].Diabet Med,1999,16:477-481.
9Diabetes Prevention Program Research Group.Effects of withdrawal from metformin on the development of diabetes in the diabetes prevention program[J].Diabetes Care,2003,26:977-980.
10Florez H,Luo J,castillo-Florez Impact of metformin-induced gastrointestinal symptoms on quality of life and adherence in patients with type 2 diabetes[J].Postgrad Med,2010,122:112-120.