胶乳增强透射免疫比浊法与电化学发光免疫分析法检测癌胚抗原结果比对

Comparison of Latex Enhanced Immunoturbidimetric Assay and Electrochemiluminescence Immunoassay for the Detection of Carcinoembryonic Antigen

目的探讨胶乳增强透射免疫比浊法与电化学发光免疫分析法检测血清中癌胚抗原的结果差异性。方法随机抽取门诊体检标本204例,用胶乳增强透射免疫比浊法和电化学发光免疫分析法同时检测血清中癌胚抗原的浓度,比较两者间差异及相关性。结果两方法学检测结果具有高度相似性,Sprerman相关性检验,相关系数为0.998。结论胶乳增强透射免疫比浊法与电化学发光免疫分析法检测值的相关性良好,胶乳增强透射免疫比浊法值得在临床上推广使用。但建议各地区基层医院实验室建立本实验室参考范围。

Objective To conduct the comparative analysis between latex enhanced immunoturbidimetry and electrochemiluminescence immunoassay in the determination of carcinoembryoric antigen. Methods 204 random samples were selected for the study. The concentration of carcinoembryonic antigen in serum was detected by both latex enhanced turbidimetry and electrochemiluminescence immunoassay. The differences and correlation between them were analyzed. Results These two methods were highly consistent. The correlation coefficient of Spearman was 0.998. Conclusion The correlation between the latex enhanced turbidimetry system and electrochemiluminescence immunoassay system is significant,suggesting that the latex enhanced turbidimetric method is worthy to popularizing in clinical practice. However,it is suggested that the reference scope of the laboratory should be established in primary hospitals in various regions.