经皮穿刺微球囊压迫术治疗原发性三叉神经痛并发症的危险因素分析

Factors related to complications after percutaneous microballoon compression in patients with primary trigeminal neuralgia

目的探讨经皮穿刺微球囊压迫术治疗原发性三叉神经痛术后并发症的影响因素。方法回顾性分析2015年12月至2017年6月经皮穿刺微球囊压迫术治疗的428例原发性三叉神经痛的临床资料。采用多因素Logistic回归分析术后并发症的危险因素。结果 428例中,术后发生并发症383例。多因素Logistic回归分析显示病程≥5年、疼痛累及三叉神经第二支、合并高血压、合并糖尿病是术后并发症的独立危险因素(P<0.05)。结论经皮穿刺微球囊压迫术原发性三叉神经痛的术后并发症发生率高,控制血压、血糖水平,并适当调整术中球囊参数,有助于减少术后并发症。

Objective To explore the factors related to the complication after the percutaneous microballoon compression in the patients with primary trigeminal neuralgia (PTN). Methods The clinical data of 428 patients with PTN undergoing percutaneous microballoon compression from December, 2011 to December 2017 were analyzed retrospectively. The factors related to the postoperative complications were statistically analyzed by multivariate Logistic regression analysis. Results Of 428 patients with PTN, 383 had postoperative complication and 45 did not. The multivariate Logistic regression analysis showed that the course of disease ≥5 years, pain involving the second branch of trigeminal nerve and associated hypertension and diabetes mellitus were the independent risk factors of the complications after the percutaneous microballoon compression in the patients with PNT (P<0.05). Conclusions The course of disease, pain involving the second branch of trigeminal nerve, hypertension and diabetes mellitus are the factors related to complications occurrence after the percutaneous microballoon compression in the patients with PTN. It is suggested that the blood pressure and blood sugar levels should be controlled during perioperative period and balloon parameters should be adjusted in order to improve the prognoses in the patients with PTN.