早期抗病毒治疗对艾滋病患者睡眠质量的影响

Observation on Changes of Sleep Quality in Patients with Early Antiviral Therapy for AIDS Patients

目的:观察和比较艾滋病患者早期抗病毒治疗后的睡眠质量变化,从而为相关临床研究和诊治实践提供参考依据。方法:选取2016年10月至2017年12月四川省攀枝花市第四人民医院感染科住院病房收治的艾滋病患者和同期来体检并自愿参加睡眠质量监测的健康人群288例,按照研究对象是否患病分为观察组(艾滋病患者)和对照组(健康人群),每组114例。对2组研究对象的匹兹堡睡眠质量指数、心理韧性量表和领悟社会支持量表得分进行比较。结果:1)观察组患者的主观睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能紊乱以及总分均明显高于对照组,且组间比较差异均有统计学意义(P <0. 05); 2)观察组患者的心理韧性量表和领悟社会支持量表得分均名明显低于对照组,且组间比较差异均有统计学意义(P <0. 05)。结论:在艾滋病患者早期抗病毒治疗的过程中,存在较为严重的睡眠质量问题,心理韧性和领悟社会支持状态均不佳,临床上要早期给予针对性的措施并进行积极预防。

Objective:To observe and compare the changes of sleep quality in patients with AIDS before and after early antiviral therapy,so as to provide reference for relevant clinical research and diagnosis and treatment practice.Methods:A total of 114 AIDS patients admitted to the inpatient ward of the Department of Infectious Diseases from October 2016 to December 2017 in Infection Department of the Fourth People′s Hospital of Panzhihua and 114 healthy subjects who came to our hospital for physical examination and volunteered to participate in sleep quality monitoring were chosen as the study object.According to whether the subjects were sick,they were divided into the study group and the control group,the study group was AIDS patients,and the control group was healthy people,and 114 cases in each group.The Pittsburgh Sleep Quality Index,the Mental Resilience Scale,and the Comprehension Social Support Scale scores were compared between the two groups.Results:1)The subjective sleep quality,sleep time,sleep time,sleep efficiency,sleep disturbance,hypnotic drugs,daytime dysfunction and total score in the study group were significantly higher than the control group,and the differences between the groups were significant.2)The scores of the psychological toughness scale and the comprehensible social support scale of the study group were significantly lower than those of the control group,and the differences between the groups were significant.Conclusion:In the process of early antiviral therapy,AIDS patients have serious sleep quality,psychological resilience and comprehensible social support status.Early targeted measures should be given and active prevention should be carried out in the clinical.