糖尿病性夏科氏关节病的影像学研究进展

Research progresses in imaging of charcot neuropathic osteoarthropathy in diabetic foot

夏科氏关节病是骨、关节和软组织的慢性进展性疾病,多由糖尿病周围神经病变所致,最常发生在足部及踝关节。由于关节稳定性下降,溃疡反复发作,该病是一种变形和破坏性过程。因此,早期诊断及鉴别CN和骨髓炎对指导治疗至关重要。通常在晚期伴发中足部溃疡情况下,易伴发骨髓炎。常规检查方法通常诊断不明确或存在误诊情况。多种MRI新技术,不但能做出较准确诊断及鉴别CN和骨髓炎,并能指导临床治疗及改善患者预后情况。作者就目前足部夏科氏关节病的影像学研究进展进行综述。

Charcot neuropathic osteoarthropathy(CN)is a chronic,progressive disease of bones,joints,and soft tissues.The disease usually occurrs in the foot and ankle as a result of diabetic peripheral neuropathy.Due to gross instability,recurrent ulcerations,it is a deforming and destructive disease process.Early diagnosis and differentiation CN from osteomyelitis are critical to guide treatment.It can exist concomitantly with osteomyelitis,typically in the setting of an advanced midfoot ulcer.Conventional examination methods often yield inconclusive or confusing data.Various advanced MR imaging protocols not only may improve the diagnostic accuracy of MR imaging and the ability of differenting CN from osteomyelitis,but also may help in making treatment decision and lead to improving patient outcomes.We aim to make a review about the recent imaging research progress in CN.