奥卡西平结合心理疗法治疗青少年癫痫120例疗效观察

Therapeutic effect of oxcarbazepine combined with psychological treatment on 120 cases of adolescent epilepsy

目的探究心理治疗与奥卡西平结合治疗青少年癫痫的临床疗效。方法选取海兴县医院2016年1月至2017年6月收治入院的青少年癫痫病人120例,按简单随机化分组分为治疗组和对照组两组,每组60例,随之进行一般资料的生活质量评分及症状自评得分后,对照组病人单纯口服奥卡西平,治疗组口服奥卡西平配合心理疗法,观察治疗后两组病人的临床治疗总有效率、不良反应发生率及症状自评得分情况。结果治疗组临床总有效率95.0%(57/60)高于对照组的75.0%(45/60),治疗组治疗后症状自评得分显著高于对照组,均差异有统计学意义(P<0.05)。治疗组的不良反应发生率(6.67%)与对照组(8.33%)比较差异无统计学意义(P>0.05)。结论临床采用奥卡西平配合心理疗法治疗青少年癫痫病人效果显著,为青少年癫痫病人的进一步治疗奠定了基础。

Objective To investigate the clinical efficacy of oxcarbazepin combined with psychotherapy in the treatment of juvenile epilepsy.Methods A total of 120 adolescent epilepsy patients admitted to Haixing County Hospital from January 2016 to June 2017 were randomly assigned into treatment group and control group,with 60 cases in each group,according to the random number table method.After the quality of life score and symptom self-assessment score,the control group was treated with Oxcarbazepine while the treatment group was treated with Oxcarbazepine combined with psychological therapy.The total efficiency,the incidence rate of adverse reaction and symptom scores of two groups were observed before treatment.Results The total effective rate of the treatment group(95%,57/60 cases)was higher than that of the control group(75%,45/60 cases),the scores of symptom self-evaluation in the treatment group were significantly higher than those in the control group,and the difference was significant(all P<0.05).The incidence of adverse reactions in the treatment group(6.67%)was lower than that in the control group(8.33%),but there was no significant difference between the two groups(P>0.05).Conclusion The clinical use of Oxcarbazepine combined with psychotherapy in the treatment of adolescents patients has a significant effect,which provide the basis for further treatment of adolescent patients with epilepsy.