胰十二指肠切除术后胰瘘研究进展

Progress in Pancreatic Fistula after Pancreaticoduodenectomy

尽管通过外科技术的改进以及围手术期管理能力的提升,胰十二指肠切除术后的死亡率已降低到1%,然而术后胰瘘的发生率仍不能使人满意。术后胰瘘的发生与胰腺组织硬度、胰管直径、肿瘤部位、术中出血量密切相关,同时也受消化道重建方式、胰管支架管的使用等影响。术后胰瘘的发生率与术后感染、出血、住院时间延长等密切相关。该文对目前胰十二指肠术后胰瘘研究进展做一综述。

Despite improvements in surgical techniques and improved perioperative management,mortality after pancreaticoduodenectomy has been reduced to 1%.However,the incidence of postoperative pancreatic fistula is still unsatisfactory.Postoperative pancreatic fistula is closely related to pancreatic tissue stiffness,pancreatic duct diameter,tumor location,intraoperative blood loss,and is also affected by digestive tract reconstruction and pancreatic duct support.The incidence of postoperative pancreatic fistula is closely related to postoperative infection,bleeding,and prolonged hospital stay.This article reviews the current progress in the study of pancreatic fistula after pancreaticoduodenal surgery.