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双刺激方案与微刺激方案对卵巢储备功能下降患者妊娠结局的影响

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摘要 目的观察双刺激方案与微刺激方案对卵巢储备功能下降患者妊娠结局的影响。方法 105例卵巢储备功能下降患者随机分为对照组与观察组,对照组52例(52个周期),观察组53例(68个周期)。观察两组基础激素水平、促排效果及妊娠结局。结果观察组D3优质胚胎率显著高于对照组,Gn用量显著少于对照组(P <0.05)。两组Gn天数、获卵数、成熟卵数、正常受精卵数、卵裂数、有效胚胎数、卵裂率、有效胚胎率均无显著差异(P> 0.05)。两组基础FSH、LH、E2水平均无显著差异(P> 0.05)。两组临床妊娠率、流产率差异无统计学意义,观察组活产率显著高于对照组(P <0.05)。结论采用双刺激方案可增加一个月经周期内获卵数、优质胚胎数,Gn用量随之增加,对促排后获卵困难的卵巢储备功能下降有一定临床意义。
作者 王燕丽
出处 《临床研究》 2019年第3期68-69,共2页 Clinical Research
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