初诊2型糖尿病经诺和锐治疗(短期强化)效果及对机体胰岛β细胞功能的影响

Effect of Novo-Rui Treatment (Short-term Intensification) in Newly Diagnosed Type 2 Diabetes Mellitus and its influence on Islet β-cell Function

目的讨论初诊2型糖尿病经诺和锐治疗(短期强化)效果及对机体胰岛β细胞功能的影响。方法回顾分析2016年4月至2017年4月我院65例初诊2型糖尿病患者的临床资料,全部患者均给予诺和锐短期强化治疗,分析患者的血糖指标、糖化血红蛋白、β细胞胰岛素抵抗指数、β细胞胰岛素分泌指数等。结果经治疗后患者的空腹血糖、餐后2h血糖、糖化血红蛋白、β细胞胰岛素分泌指数、β细胞胰岛素抵抗指数等指标均较治疗前明显好转,且差异明显,具有统计学意义(P<0.05)。结论诺和锐短期强化治疗对改善初诊2型糖尿病患者的胰岛β细胞功能具有重要意义,并有助于提高血糖控制效果,对改善患者的预后质量具有重要意义,值得在临床上广泛应用和推广。

OBJECTIVE To discuss the effects of Novo-Rui treatment (short-term intensive) on newly diagnosed type 2 diabetes and on pancreatic β-cell function. METHODS The clinical data of 65 patients with newly diagnosed type 2 diabetes mellitus in our hospital from April 2016 to April 2017 were retrospectively analyzed.All patients were given Novoreotide short-term intensive therapy.The patients′ blood glucose,glycosylated hemoglobin,β-cell insulin resistance index,β-cell insulin secretion index. RESULTS After treatment,the fasting blood glucose,2-hour postprandial blood glucose,glycosylated hemoglobin,β-cell insulin secretion index,β-cell insulin resistance index and other indicators were significantly better than before treatment,and the difference was statistically significant( P <0.05). CONCLUSION Nuo-Rui-Rui short-term intensive treatment of patients with newly diagnosed type 2 diabetes,pancreatic β-cell function is important,and help to improve blood sugar control effect,to improve the prognosis of patients with quality of great significance,it is widely used in clinical and promotion.