不同性别间尿路感染病原体分布及耐药性的差异性分析

Differential Analysis of Pathogen Distribution and Drug Resistance of Urinary Tract Infections between Different Gender

目的该次研究旨在研究尿路感染患者的病原体的分布情况与耐药性的差异与性别之间的关系。方法对该院在2015年1月—2018年1月,这一期间内收治的患者随机抽取出98例患者,作为研究目标,根据患者的性别进行分组,其中有23例患者为男性患者,将其分成A组,余下的75例患者为女性患者,将其分为B组,鉴别分离出来的病原体的种类,进行体外药物敏感试验,然后根据病原体的种类以及试验结果对性别不同的患者的病原体的分布情况以及耐药性的差异情况展开深入研究。结果 A组患者的标本的阳性率为44.44%,B组患者的标本的阳性率为51.11%;一共检出10种病原体,其中,两组患者分布情况最多的病原体均为大肠埃希菌,A组达到了28.89%(13/45),B组达到了41.82%(23/55),B组患者大肠埃希菌的分布情况高于A组,余下的9种病原体,B组的分布水平均低于A组,差异有统计学意义(P<0.05);A组患者的耐药性要显著高于B组患者,不管B组患者在肠球菌方面的耐药性要该与A组,B组四环素的耐药率达到了66.5%,而A组四环素的耐药率为43.6%,组间差异有统计学意义(P<0.05)。结论男性与女性患者检出率最高的病原体为大肠埃希菌,且女性的检出率高于男性,其余病原体均为男性检出率高于女性,男性的耐药性普遍高于女性,但就肠球菌的耐药性而言,男性要低于女性。

Objective This study was designed to investigate the relationship between the distribution of pathogens and drug resistance in patients with urinary tract infections and gender. Methods From January 2015 to January 2018, 98 patients were randomly selected from our hospital during the period. As a research target, the patients were divided according to their gender. Among them, 23 patients were male patients. They were divided into group A, and the remaining 75 patients were female patients. They were divided into group B, and the isolated pathogens were identified for in vitro drug sensitivity test. Then, according to the type of pathogen and the test results, patients with different genders were selected. The distribution of pathogens and the differences in drug resistance were studied in depth. Results The positive rate of specimens in group A was 44.44%, and the positive rate in specimens of group B was 51.11%. A total of 10 pathogens were detected. The pathogens with the most distribution were Escherichia coli. Group A reached28.89%(13/45), and group B reached 41.82%(23/55). The distribution of Escherichia coli in group B was higher than that in group A, and the distribution of the remaining 9 pathogens and group B. All were lower than group A, the difference was statistically significant(P<0.05);the drug resistance of group A was significantly higher than that of group B, regardless of the resistance of group B to enterococci. In group A, the resistance rate of tetracycline in group B reached 66.5%, while the resistance rate of tetracycline in group A was 43.6%. The difference between groups was statistically significant(P<0.05). Conclusion The pathogen with the highest detection rate of male and female patients is Escherichia coli, and the detection rate of females is higher than that of males. The detection rate of males in other pathogens is higher than that of females. The drug resistance of males is generally higher than that of females. However,in terms of drug resistance of Enterococcus, men are lower than women.