红细胞单采术治疗真性红细胞增多症的效果分析与护理

Analysis and Nursing of Erythrocyte Apheresis in the Treatment of Polycythemia Vera

目的在真性红细胞增多症患者中应用红细胞单采术予以治疗,探究分析其效果和护理措施。方法于2017年3月—2018年7月展开,在该时间段从该院选取40例真性红细胞增多症患者进行探究分析,所有患者均采用MCS+全自动血细胞分离仪展开红细胞单采术治疗,对去除红细胞的血液学参数和不良反应发生情况进行分析。结果相较于治疗前,患者治疗后的红细胞、血红蛋白含量以及红细胞压积值均有所降低,其中治疗前红细胞、血红蛋白含量以及红细胞压积值分别为(7.81±1.21)×10^(12)/L、(221.86±31.82)g/L、(66.85±9.73)%,治疗后的红细胞、血红蛋白含量以及红细胞压积值分别为(6.65±1.32)×1012/L、(158.00±14.69)g/L、(48.89±4.30)%,差异有统计学意义(t=3.261 5、5.261 3、4.231 5,P<0.05)。结论在真性红细胞增多症患者中应用红细胞单采术予以治疗的效果显著,且安全性较高,临床推广价值显著。

Objective To treat the patients with polycythemia vera with erythrocyte apheresis, and to analyze its effects and nursing measures. Methods From March 2017 to July 2018, 40 patients with polycythemia vera were enrolled in our hospital during this time period. All patients were treated with MCS+ automatic blood cell separator for erythrocyte apheresis. Hematological parameters and adverse reactions occurred in the removal of red blood cells were analyzed.Results Compared with that before treatment, the red blood cell, hemoglobin content and hematocrit value of patients decreased after treatment. The red blood cell, hemoglobin content and hematocrit value before treatment were(7.81 ±1.21)×10^12/L,(221.86±31.82) g/L,(66.85± 9.73)%, red blood cell, hemoglobin content and hematocrit value after treatment were(6.65±1.32)×10^12/L,(158.00±14.69) g/L,(48.89± 4.30)%, the different was statistically significant(t=3.261 5,5.261 3, 4.231 5,P<0.05). Conclusion The application of erythrocyte apheresis in the treatment of patients with polycythemia has a significant effect, and it has high safety and significant clinical promotion value.