慢性鼻-鼻窦炎术后五黄液灌洗疗效研究

Study on nasal lavage with Wuhuang decoction after surgery for chronic rhino-sinusitis

目的探讨中药五黄液在慢性鼻-鼻窦炎术后鼻腔灌洗治疗中的优化方案。方法选取2017年4-12月西南医科大学附属中医医院耳鼻咽喉科诊断为慢性鼻-鼻窦炎并经鼻内镜手术的患者45例,并随机分为治疗1组、治疗2组和治疗3组,每组15例,均使用五黄液灌洗鼻腔。分别于灌洗半个月、灌洗1个月及术后3个月时行患者自觉症状评分、患者对鼻腔灌洗耐受程度评分、鼻内镜Lund-Kennedy评分。结果在灌洗半个月、灌洗1个月及术后3个月时,治疗1组和治疗2组患者自觉症状评分、鼻内镜检查Lund-Kennedy评分低于治疗3组,差异均有统计学意义(P<0.05);在灌洗1个月及术后3个月时,治疗1组和治疗2组患者自觉症状评分比较,差异无统计学意义(P>0.05)。在灌洗1个月时,治疗2组患者对鼻腔灌洗耐受程度评分低于治疗1组和治疗3组,差异有统计学意义(P<0.05)。结论慢性鼻-鼻窦炎术后鼻腔灌洗治疗的最优方案为前半个月每天灌洗1次,之后隔天灌洗1次。

Objective To explore the optimal scheme of Chinese medicine Wuhuang decoction for nasal lavage after operation of chronic rhino-sinusitis. Methods 45 patients with chronic rhino-sinusitis diagnosed by otorhinolaryngology Department of the Affiliated Hospital of Traditional Chinese University from April to December 2017 were selected and randomly divided into treatment group 1,treatment group 2 and treatment group 3,each group of 15 patients,who were treated with Wuhuang decoction for nasal lavage.The scores of conscious symptoms,tolerance to nasal lavage and endoscopic Lund-Kennedy were given at half month,one month and three months after operation respectively. Results At half a month of lavage,one month of lavage and three months after operation,the scores of conscious symptoms and Lund-Kennedy scores of nasal endoscopy in the treatment group 1 and the treatment group 2 were lower than those in the treatment group 3,and the differences were statistically significant( P < 0.05 ).At 1 month of lavage and 3 months after operation,there was no significant difference in the scores of conscious symptoms between the treatment group 1 and the treatment group 2( P >0.05).At 1 month of lavage,the tolerance score of nasal lavage in the treatment group 2 was lower than that in the treatment group 1 and the treatment group 3,and the difference was statistically significant( P <0.05). Conclusion The best treatment for chronic rhino-sinusitis after operation is to lavage once a day in the first half month and once every other day.