101例儿童基底节区病变分析

Clinical analysis of 101 children with basal ganglia lesions

目的探讨基底节区病变的临床特点及病因分析,加强对本症的认识。方法:选取住院的101例存在基底节区病变患儿的发病过程及诊治转归过程,对患者的临床特点、影像学、电生理资料及化验结果进行分析总结。结果:101例存在基底节区病变的病例中,有脑炎34例,中枢神经系统脱髓鞘病变13例,免疫系统疾病合并中枢神经系统损害5例,缺血、缺氧和中毒性疾病22例,代谢性疾病6例,内分泌疾病3例,脑梗死13例,先天发育性疾病及其他病因5例。结论:基底节区病变的临床表现多样,病因复杂多样,通过对本组疾病的总结,有助于提高对本组疾病的认识和诊断。

Objective To explore the clinical characteristics and the etiology of basal ganglia lesions,in order to strengthen the understanding and diagnosis of this disease.Method To collect 101 children with basal ganglia lesions and analyze the clinical characteristics,neuroimaging,electrophysiology data and laboratory tests.Results The etiologic diagnoses for 101 cases were 34 cases as encephalitis,13 cases as demyelinating disorders of central nervous system,5 cases as the immune system diseases combined with central nervous system damage,22 cases as hypoxic ischemia encephalopathy and toxic diseases,6 cases as metabolic diseases,3 cases as endocrine diseases,13 cases as brain infarctions,and 5 cases as congenital developmental disorders and other diseases.Conclusion The clinical manifestations and the etiology of the basal ganglia lesions are diversiform,and to summarize the cases can help improve the understanding and diagnosis of this disease.