合成类蛋白酪氨酸磷酸酶1B抑制剂专利现状分析

Analysis of the patents about PTP1B inhibitors

蛋白酪氨酸磷酸酶1B(PTP1B)是治疗2型糖尿病的潜在的重要靶点,与肥胖、肿瘤也具有密切关系,本文从专利分布和布局的角度出发,选择以蛋白酪氨酸磷酸酶1B抑制剂作为主题,使用关键词对全球专利数据库中的全球发明专利申请进行了检索,得到相关的发明专利申请,对上述数据进行人工筛选分类,重点对合成类蛋白酪氨酸磷酸酶1B抑制剂专利态势作了研究分析,以期能够为该领域药物的开发与仿制提供有益的借鉴与参考。

Protein tyrosine phosphatase 1B (PTP1B) is a potential important target for the treatment of type 2 diabetes,and is closely related to obesity and tumors.By analyzing the patent distribution for PTP1B inhibitors,especially focusing on the patent situation and representative patents of the synthetic PTP1B inhibitors,we provided useful information on how to utilize and operate pharmaceutical patents for domestic drug development.