血清降钙素原水平评价早产儿院内感染程度与预后的研究

Serum Procalcitonin Level Evaluation of Nosocomial Infection and Prognosis in Preterm Infants

目的研究血清降钙素原水平评价早产儿院内感染程度与预后。方法方便选取2018年1月—2016年1月在该院发生院内感染的68例早产儿作为研究对象,均对其进行血清降钙素原水平检测,根据检测结果将其分为轻度感染组、中度感染组和重度感染组,对3组患儿的新生儿危重评分进行测定,并对3组患儿的预后效果进行观察分析。结果通过68例患儿的血清降钙素原水平评价分析,26例为轻度感染组,23例为中度感染组,19例为重度感染组,重度感染组的血清降钙素原水平均高于轻度感染组和中度感染组,中度感染组的血清降钙素原水平高于轻度感染组,差异有统计学意义(P<0.05)。比较3组患儿的新生儿危重评分发现,重度感染组的评分均低于轻度感染组和中度感染组,中度感染组的评分低于轻度感染组,差异有统计学意义(P<0.05)。比较3组患儿的预后情况发现,轻度感染组的存活率均高于中度感染组和重度感染组,中度感染组的存活率高于重度感染组,组间差异有统计学意义(P<0.05)。结论通过对发生院内感染早产儿血清降钙素原水平分析可对其感染程度进行有效鉴别区分,从不同感染程度的患儿预后情况观察发现,感染越严重患儿的存活率越低。

Objective To study the serum procalcitonin level and evaluate the degree of nosocomial infection and prognosis in premature infants.Methods 68 premature infants with nosocomial infection in our hospital were selected as subjects from January 2016 to January 2018.All of them were tested for serum procalcitonin level.According to the test results,they were divided into mild infection group,moderate infection group and severe infection group.The neonatal critical scores of the three groups were measured,and the prognostic effects of the three groups were observed and analyzed.Results Serum procalcitonin levels were evaluated in 68 children,26 were mild infection,23 were convenient moderately infected,19 were severely infected,and serum procalcitonin was high in severely infected group.In the mild infection group and the moderate infection group,the serum procalcitonin level in the moderate infection group was higher than that in the mild infection group.The difference between the groups was significant(P<0.05).Comparing the neonatal critical scores of the three groups,the scores of the severe infection group were lower than those of the mild infection group and the moderate infection group.The scores of the moderate infection group were lower than those of the mild infection group.The differences between the groups were significant(P<0.05).Comparing the prognosis of the three groups,the survival rate of the mild infection group was higher than that of the moderate infection group and the severe infection group.The survival rate of the moderate infection group was higher than that of the severe infection group.Differences between groups were significant(P<0.05).Conclusion By analyzing the serum procalcitonin level in premature infants with nosocomial infection,the degree of infection can be effectively differentiated.The prognosis of children with different infection levels shows that the more severe the infection,the lower the survival rate.