依达拉奉联合阿司匹林对急性脑梗死患者血小板抑制率及神经功能的影响

Effects of Edaravone Combined with Aspirin on Platelet Inhibition Ratio and Neurological Function in Patients with Acute Cerebral Infarction

目的分析依达拉奉联合阿司匹林对急性脑梗死患者血小板抑制率及神经功能的影响。方法选取2015年8月～2017年8月我院收治的88例急性脑梗死患者为研究对象,按随机数字表法分为观察组及对照组各44例,对照组给予口服阿司匹林治疗,观察组在对照组基础上予以口服依达拉奉治疗,比较两组患者的血小板抑制率以及神经功能变化情况。结果观察组治疗后的AA途径抑制率、ADP受体抑制率均较对照组高,NIHSS评分较对照组低,治疗总有效率高于对照组,组间差异均有统计学意义(P<0.05)。结论依达拉奉联合阿司匹林治疗急性脑梗死,能有效提升血小板抑制率,改善神经功能,提高临床疗效。

Objective To analyze the effect of edaravone combined with aspirin on platelet inhibition ratio and neurological function in patients with acute cerebral infarction.Methods 88 cases of acute cerebral infarction patients as the research object from August 2015 to August 2017 of our hospital,according to random number table method were divided into observation group and the control group (each n =44).The control group was given oral aspirin therapy,the observation group was given the edaravone oral treatment on the basis of control group,and compared two groups of patients of platelet inhibition rate and changes in neural function.Results After treatment the AA approach inhibition rate and ADP receptor inhibition rate of observation group are higher than the control group.The NIHSS score of observation group was lower than those of control group.The total effective rate of observation group was higher than the control group.The differences between the two groups were statistically significant ( P <0.05).Conclusion Edaravone combined with aspirin in the treatment of acute cerebral infarction can effectively increase the rate of platelet inhibition,improve neurological function and improve clinical efficacy.