汾阳市新确诊高血压患者合并高尿酸血症情况及影响因素分析

Prevalence of hyperuricaemia and its associated factors in newly diagnosed hypertensive patients in Fenyang

目的调查新诊断高血压患者中高尿酸血症患病率及其危险因素。方法对汾阳市4个社区539例新确诊高血压患者进行问卷调查,并收集体格检查以及实验室检查结果。结果新诊断高血压患者中高尿酸血症患病率为21. 8%。多因素分析结果显示:年龄> 55岁(调整OR=1. 65,95%CI 1. 12-2. 29),高血压家族史(调整OR=1. 65,95%CI 1. 01-2. 67),腰围超标(调整OR=1. 60,95%CI 1. 12-2. 29),低密度脂蛋白胆固醇增高(调整OR=1. 33,95%CI 0. 97-1. 82),甘油三酯增高(调整OR=1. 63,95%CI 1. 01-2. 65)为高血压患者合并高尿酸血症的风险因素。结论高血压患者中高尿酸血症患病率较为普遍,其发生可能与血脂紊乱及肥胖密切相关。

Objective To assess the prevalence of factors associated with hyperuricaemia among newly diagnosed hypertensive patients.Methods A total of 539 newly diagnosed hypertensive patients from 4 communities in Fenyang were enrolled in this study.Information about demographic characteristic,physical examination and laboratory test results were collected.Results The prevalence of hyperuricaemia was 21.8%in newly diagnosed hypertensive patients.The risk factors associated with hyperuricaemia included age>55 years[adjusted odds ratio(AOR)1.65,95%CI 1.12-2.29],family history of hypertension(AOR=1.65,95%CI 1.01-2.67),increased waist circumference(AOR=1.60,95%CI 1.12-2.29),increased low-density lipoprotein cholesterol(AOR=1.33,95%CI 0.97-1.82)and triglycerides(AOR=1.63,95%CI 1.01-2.65).Conclusion Hyperuricaemia is common among newly diagnosed hypertensive patients and is associated with dyslipidemia and obesity.