肠道微生物群在妊娠期肥胖及糖尿病中的作用

Role of gut microbiota in gestational obesity and diabetes mellitus

肠道微生物群是定植在人体肠道内的全部微生物及其基因的统称。近年来研究发现,肠道微生物群的改变与妊娠期肥胖及糖尿病的发生、发展密切相关。肠道微生物群的改变可能通过影响某些代谢机制影响相关疾病的发生、发展,其具体的分子生物学机制尚不明确。文章对肠道微生物群在妊娠期肥胖及糖尿病中的作用进行综述。

Gut microbiota is a general term for all microorganisms and their genes that are colonized in human intestine.In recent years,studies have found that the changes in gut microbiota are related to the development of gestational obesity and diabetes mellitus.The changes in gut microbiota may affect the occurrence and development of related diseases by affecting certain metabolic mechanisms.However,the specific molecular biological mechanisms have not been thoroughly studied.Therefore,this review focuses on the role of gut microbiota in gestational obesity and diabetes mellitus.