阿坝州藏区人群幽门螺杆菌感染流行病学调查及相关影响因素分析

Epidemiological investigation and related factors analysis of Helicobacter pylori infection in Tibetan population at Aba Prefecture

目的调查阿坝藏区人群幽门螺杆菌(Hp)的感染现状,分析相关影响因素,为藏区防治Hp感染提供依据。方法在四川省阿坝州自然村落招募志愿者,进行C14尿素呼气试验检测Hp感染情况,并给予问卷调查。结果共544名进入Hp感染现状与其影响因素的分析。Hp感染率为30. 5%,男性与女性无明显差异(P> 0. 05)。不同年龄阶段的人群Hp感染率差异有统计学意义(P <0. 05)。Hp感染与饮食习惯相关,饮酒及喜吃酸菜者感染率高于对照组(P <0. 05)。多元逻辑回归显示Hp感染的独立危险因素为年龄和凉菜。结论藏区人群Hp感染呈相对低感染率状态,饮酒及喜吃酸菜明显增加Hp感染率。年龄和凉菜是Hp感染的独立危险因素。

Objective To investigate the current situation of Helicobacter pylori(H p)infection in Aba Tibetan area and analyze the related influencing factors,so as to provide the basis for prevention and treatment of Hp infection in Aba Tibetan area.Methods We recruited resident villagers in the villages of Aba Tibetan Autonomous Prefecture to test the Hp infection by using the 14C-urea breath test and gave a questionnaire survey.Results A total of 544 cases of Hp infection and their influencing factors were analyzed.The infection rate of Hp was 30.5%.There was no significant difference between males and fem ales(P>0.05).The difference of Hp infection rate between different age groups was statistically significant(P<0.05).Hp infection was correlated with dietary habits.The infection rate of people who drank alcohol and liked pickles was significantly higher than that of the control group(P<0.05).Multivariate logistic regression analysis showed that the independent risk factors for Hp infection were age and lettuce.Conclusion Hp infection in Tibetan population shows a relatively low infection rate.Their Hp infection is related to drinking sauerkraut.Age and lettuce are independent risk factors for Hp infection.