热层析在乳腺疾病诊疗中的临床应用进展

Progress on application of thermal tomography in the diagnosis and treatment of breast diseases

人体内细胞不断的新陈代谢可以产生热辐射,组织的病理改变使局部新陈代谢发生变化,进而导致局部的热辐射发生相应的改变。热层析成像技术通过对人体组织的热分布变化的检测,运用Pennes生物传热方程,寻找热辐射与疾病的内在联系,进行医学研究与临床诊断。热层析成像技术在中、西医都有相关临床应用,成为临床工作中的补充影像技术。在乳腺疾病方面,该技术可以进行疾病早期检出并做出初步诊断;另外对于局部晚期乳腺癌新辅助化疗的患者,可以一定程度上监测瘤体对于化疗药物的疗效反应。文章就热层析在乳腺疾病的临床应用现状及进展予以综述。

The continuous metabolism of cells in the human body can produce thermal radiation, and the pathological changes of tissues can cause changes in local metabolism, which leads to the corresponding changes of local thermal radiation. Thermal tomography technology can be used to detect the change of heat distribution in human tissues and then find the internal relationships between heat radiation and disease via Pennes bio- heat transfer equation, so as to perform medical research and clinical diagnosis. Thermal tomography has been used in both traditional Chinese medicine and western medicine as a complementary imaging technique in clinic. In the case of breast diseases, thermal tomography can detect the disease at early stage and make a preliminary diagnosis. In addition, thermal tomography can monitor the tumor response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. Herein the application and development of thermal chromatography in breast disease are reviewed.