电子释药胶囊智能给药驱动装置的仿真与设计

Simulation and design of an intelligent drug delivery driving device of electronic capsule

为了实现胃肠道电子释药胶囊的释药剂量、释药时间的智能控制,设计驱动力智能可调的电磁线圈-双永磁体驱动装置,以实现电子胶囊给药驱动力的准确控制。为建立给药驱动力F、电磁线圈行程d、激磁电流I的数学模型,实现驱动力的可控,设计给药驱动装置的原理样机,搭建给药驱动力测试平台。采用Polynomial理论建立给药驱动力数学模型,对比不同参数的驱动力模型对应的R^2(R-square)、均方根误差,选用I、d的最高次幂分别为1次幂、5次幂构建的数学模型达到最优的拟合精度。根据拟合模型,由激磁电流调节模块实时改变电磁线圈的激磁电流,实现释药剂量、释药时间的可控。由实验验证可知:给药驱动力模型正确可行,为释药驱动力的智能可调提供理论基础。

An intelligently adjustable drug delivery driving device based on electromagnetic coil-double permanent magnet is designed to realize the intelligent control of release dosage and release time of electronic capsules for gastrointestinal diseases. A mathematical model based on drug delivery driving force F, electromagnetic coil stroke d, and exciting current I is established to achieve controllable driving force. Moreover, a prototype of the drug delivery driving device is designed, and a platform for the test of drug delivery driving force is set up. The mathematical model of drug delivery driving force was established using Polynomial theory. The R^2 (R-square) and root mean square error of the driving force model with different parameters were compared. When the highest power of I and d were chosen to be 1 power and 5 power, respectively, the fitting accuracy of the mathematical model is the best. According to the fitting model, the real-time excitation current of the electromagnetic coil was adjusted by excitation current adjustment module, so as to achieve the controllable release dosage and release time. The experimental verification showed that the driving force model is correct and feasible, providing a theoretical basis for the intelligent adjustment of drug delivery driving force.