基于肠道菌群探讨针刺治疗多囊卵巢综合征

Acupuncture Treating PCOS Based on Intestinal Flora

多囊卵巢综合征(PCOS)临床表现以月经失调、胰岛素抵抗、高雄激素血症、排卵障碍以及代谢异常为主,作为一种常见的内分泌代谢紊乱与生殖功能障碍性疾病,引起了中西医学者的共同关注。"肠道菌群"的观点源于现代医学,被视为"肠脑器官"。针刺可以通过作用于不同穴位而改变特定的肠道菌群分布,提高有益菌含量,维持人体内外环境的平衡,从而降低PCOS发病的几率。现采用中西医结合的方式,基于肠道菌群的内在因素,探讨针刺在沟通内外、维护正气、抗御外邪3个方面治疗多囊卵巢综合征的作用机制。

The clinical manifestations of polycystic ovary syndrome(PCOS) are mainly menstrual disorders, insulin resistance, hyperandrogenemia, ovulation disorders and metabolic abnormalities. As a common endocrine metabolic disorder and reproductive dysfunction disease, PCOS has attracted the common attention of Chinese and western medical scholars. The idea of intestinal flora is originated from modern medicine and is considered as “intestinal brain organ”. Acupuncture can change the distribution of specific intestinal flora by acting on different acupoints, it can improve the content of beneficial bacteria and maintain the balance between the internal and external environment of human body, thus to reduce the incidence of PCOS. Based on the internal factors of intestinal flora, this study explored the mechanism of acupuncture in the treatment of PCOS in terms of internal and external communication, maintenance of vital qi , and resistance to external pathogens.