卡前列素氨丁三醇、卡孕栓和缩宫素联合应用治疗产后出血的效果

Effect of combined application of Carboprost Tromethamine, Carboprost Suppository and Oxytocin in the treatment of postpartum hemorrhage

目的探讨卡前列素氨丁三醇、卡孕栓和缩宫素联合应用治疗产后出血的效果。方法选取本院2015年8月～2018年8月收治的40例顺产产后出血高危患者作为研究对象,按照入院时间不同分为对照组(20例)与观察组(20例)。对照组采用缩宫素联合卡孕栓进行治疗,观察组采用卡前列素氨丁三+缩宫素+卡孕栓进行治疗。比较两组产后、产后2 h、产后24 h的出血量以及总出血量、24 h血红蛋白下降情况,并对比两组的不良反应总发生率。结果两组患者的不良反应总发生率比较,差异无统计学意义(P>0.05)。观察组患者的产后出血量、产后2、24 h出血量及总出血量均少于对照组,差异有统计学意义(P<0.05)。观察组患者的产后24 h血红蛋白下降值明显低于对照组,差异有统计学意义(P<0.05)。讨论在产后出血高危患者中,使用卡前列素氨丁三醇、缩宫素、卡孕栓的治疗效果明显优于缩宫素联合卡孕栓治疗效果,能够显著减少产妇产后出血量,临床疗效确切而且不会对患者健康产生较大影响,应用效果满意,值得推荐。

Objective To explore the effect of combined application of Carboprost Tromethamine,Carboprost Suppository and Oxytocin in the treatment of postpartum hemorrhage. Methods A total of 40 cases of high risk of postpartum hemorrhage in our hospital from August 2015 to August 2018 were selected as the research objects. According to the time of admission,they were divided into the control group (20 cases) and the observation group (20 cases). The control group was treated with Oxytocin combined with Carboprost Suppository,and the observation group was treated with Carboprost Tromethamine+Carboprost Suppository +Oxytocin. The amount of bleeding after delivery,2 hours after delivery and 24 hours after delivery,the total amount of bleeding and the decrease value of hemoglobin in 24 hours after delivery were compared between the two groups,and the total incidence of adverse reactions was compared between the two groups. Results There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). The amount of bleeding during and after operation in the observation group was less than that in the control group,with significant difference (P<0.05). The decrease of hemoglobin in 24 hours in the observation group was significantly lower than that in the control group,with significant difference (P<0.05). Conclusion In the high-risk patients of postpartum hemorrhage,the therapeutic effect of using Carboprost Tromethamine,Oxytocin and Carboprost Suppository is obviously better than that of Oxytocin combined with Carboprost Suppository. It can significantly reduce the amount of postpartum hemorrhage of parturients. The clinical effect is exact and will not have a greater impact on the health of patients. The application effect is very satisfactory. It is worth recommending.